Giles is from San Francisco, receiving his bachelor’s degree in Molecular and Cell Biology from the University of California, Berkeley. In 1994, he came to Cambridge, becoming a member of Wolfson College and joining the lab of Prof Sydney Brenner for his PhD studies. In 1998 he began his postdoctoral training with Professor Stephen O’Rahilly in the Department of Clinical Biochemistry, working on the genetics of severe human obesity.
Giles is now a Principal Research Associate and group leader at the University Metabolic Research Labs, studying brain control of food intake and bodyweight. He is also director of the Genomics and Transcriptomics core facility.